1.STI/HIV INFECTIONS HIV shedding from the female genital tract. Evaluation of Recruitment and testing strategies for HIV-1 discordan couples in Kenya. Bacterial vaginosis, a randomized intervention trial to reduce recurrence. HIV shedding from the Female Genital Tract Phase III Randomized placebo-control trial of HSV-2 suppression to prevent HIV transmission among HIV-discordant couples.    2.DIARRHOEAL DISEASES      Epidemiology study of infectious diarrhoeal diseases in children in a Coastal rural area of Kenya. Virulence properties and serotypes of Shiga toxin Escherichia coli  from diarrhoeal patients in Kajiado and Narok Districts of Kenya. Case control study to investigate risk factors for invasive Salmonellosis in Children.   3.OPPORTUNISTIC INFECTIONS  Phenotyping molecular, immuno-biomedical characterization and antifungal drug susceptibility of cryptococcus species from clinical sources in Nairobi, Kenya. Mycological investigation of HIV/AIDS oral candidiasis and antifungal drug resistance. 4.EMERGING INFECTIONS  Epidemiology of Cryptosporidium in Children: Identification and genetic diversity.

5.PARASITOLOGY Field evaluation of a new urine-based ELISA test, and development of other formats of Immunodiagnostics for Lympatic Filariasis in Coastal Kenya. School health education and chemotherapy in the control of soil transmitted  Helminthiasis and Schistosomiasis in Kwale. Soil transmitted Helminths and Schistosoma mansoni control in Mwea Division school-based deworming programme. National Elimination of Lymphatic Filariasis (with the Ministry of Health).   6.ENTOMOLOGY   (i) Trends in transmission and Infection with Anopheline-Transmitted Lymphatic Filariasis. (ii) Evaluation of antifilarial regimens in reduction of infection and effect on survival and Anopheline mosquitoes.  7.TRAVEL MEDICINE Epidemiology of human enterotoxigenic Escherichia coli and other bacteria enteropathogens isolated from food handlers working in tourist hotels in Nairobi and the Coast of Kenya.