CENTER CLINICAL RESEARCH (CCR)-NAIROBI

KEMRI Centre for Clinical Research

Overview

The Centre for clinical research (CCR) was established in 1985 as a clinical trials unit to support development of drugs and vaccines aimed at tackling priority disease conditions in the country. It has grown over time and established linkages with key institutions and partners notably the United States Medical Research Unit (USAMRU) , Drugs for Neglected Diseases Initiative (DNDi), where KEMRI is a founding member, the University of Washington,  Foundation for Innovative New Diagnostics (FIND) , University of Texas Medical Branch (UTMB).The centre scientists have undertaken numerous clinical trials initially these were for the treatment of leishmaniasis (kala azar) in children. During this inception years, CCR was a must visit site for the university of Nairobi Medical students to understand the value of research in drug development and the appropriate treatment of patients

READMORE

Mission

To improve human health and quality of life through research, capacity building and service delivery

Vision

To be a globally recognized Centre of excellence in human health research.

Mandates

  1. Undertake research in communicable and Non communicable diseases.
  2. Provide a platform for clinical trials (drug safety and efficacy) in neglected, communicable and non-communicable diseases.
  3. Provide a conducive environment for patient/ participant monitoring, support and safety. READMORE.

Products and services offered

  1. Laboratory diagnostics
  2. Diagnostic imaging services. General X-Ray and Ultrasonography
  3. Endoscopy services
  4. General outpatient services
  5. Pharmacy dispensing services
  6. Catering services
  7. Laundry services

Functions

  1. Undertake research in Communicable and Non-Communicable Diseases
  2. Provide a platform for clinical trials (drug safety and efficacy) in Neglected, Communicable and Non-Communicable Diseases
  3. Provide a conducive environment for patient/participant monitoring, support and safety
  4. Test new therapies, tools and vaccines for new therapies READMORE.

Divisions

  1. CLINICAL TRIALS DIVISION.

Clinical trials are undertaken at the Nairobi Station and the county stations of Thika, Kisumu, Kericho. The competencies that are established for clinical trials include, Data Management Capacity, Clinical Research Laboratories, Community Advisory Boards, Research Oversight / Governance, Trial Operational Management and Regulatory Support. READMORE

Ongoing Projects

  • A demographic surveillance system (DSS) in the previous bed net study area aimed at establishing a high quality surveillance system in a population of 135,000 and provide an infrastructure that will yield reliable demographic
    data and serve as a platform to evaluate the impact of public health interventions on morbidity and mortality.
  • Population genetics of malaria vectors.
  • The effects of climate change on human health.
  • The epidemiology and immunology of malaria epidemics in the highlands. READMORE

Completed Projects

  • A community-based trial on the impact of insecticide-treated bed nets on childhood morbidity and mortality in an area of intense and perennial malaria transmission in western Kenya,
  • The interaction of malaria and HIV in pregnant women and the immuno-epidemiology of malaria in western Kenya,
  • The Asembo Bay Cohort Project.

CLICK ON PROFILE PHOTO TO VIEW FULL PROFILE

Dr. Veronica Kemunto Manduku


Deputy Director Centre For Clinical Research
Dr. Veronica Manduku is the Deputy Director, Centre for Clinical Research and has a background in diagnostic imaging. She holds a Bachelor’s degree in Medicine and Surgery from Pune University, India (1996) and a Masters in Medicine in Diagnostic Imaging from the University of Nairobi (2003). As a director, she coordinates a robust research team with expertise in clinical trials, epidemiology and basic sciences within several research stations including the Nairobi, Kisumu, Kericho and Thika counties. The team typically undertakes research in key infectious diseases like HIV, Malaria, Leishmaniasis, Sickle cell disease and a good number in Non-Communicable Diseases (NCDs) like Mental and dental health, cancer, child and adolescent health, reproductive health among others

DR SIMON NJENGA


Dr. Njenga is a Paediatrician and Medical researcher with experience in conducting Clinical trials and Epidemiological studies. In KEMRI, Dr. Njenga has substantively contributed to scientific review process for over 15 years and has researched on and managed clinical Paediatric HIV for more than 20 years cumulatively

– Research Grants/Current/Previous last three (3) years.
1. The Double Burden of Malnutrition: Prevalence, Associated Risk Factors and the Impact of Multiple Micronutrient Supplementation Children 3-10 Years Old. A GOK grant…….

DR. BENSON SINGA


Benson Singa is a research scientist at the Kenya Medical Research Institute’s, Centre for Clinical Research, Reproductive Health Research Unit. He has been a close collaborator on several studies of helminth, malaria, STI and HIV co-infection over the past years including programmatic evaluation.
Dr. Singa has served as a Principal Investigator (PI), a co-investigator and a medical coordinator on these studies. Singa’s background interest is in Public Health especially Sexual Reproductive Adolescent and Child Health (SRACH). These interest encompass both preventive, promotive and curative services….

DR. JANE MBUI


In the division the mandate is to undertake research in Neglected Tropical Diseases (NTD’s) with special emphasis of Visceral Leishmaniasis (VL) which is the most serious form of the disease. The team are involved in research to understand the immunology of the disease as it is known that only a small fraction of those infected persons go to develop the disease. We are also partnering with other institutions in the region as members of the Leishmainia East Africa Platform (LEAP) to undertake multicenter studies in clinical trials looking for safer, shorter and efficacious treatments for VL…..

DR LINNET ONGERI


Dr. Linnet Ongeri is a researcher in the field of mental health working at the Centre for Clinical Research in the Kenya Medical Research Institute (KEMRI) and a current postdoctoral fellow in the Global Initiative for Neuropsychiatric Genetics Education in Research (GINGER) program, hosted jointly by the Harvard T.H. Chan School of Public Health and the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard.
Having worked in Kenya for the last 10 years as a medical doctor and later as a psychiatrist, Dr. Ongeri has gained meaningful experience and understanding of the dire needs of the mentally ill in Kenya. ..

DR. PHELGONA APONDI OTIENO


Dr. Phelgona Apondi Otieno is Principal Research Officer
A paediatrician and epidemiologist with long standing experience in clinical work, medical research, mentorship in medical research and leadership. She has vast clinical experience which she first attained at the Kenyatta National Teaching and Referral Hospital rotating in all departments with a focus in paediatrics during the years of specialization.
Her medical research spans various fields including, HIV and Maternal HIV disease progression, HIV PMTCT, child health projects, Preterm Birth Initiative programs among other fields.

Dr Samuel Gathere


Dr Samuel Gathere is a senior clinical research scientist at the KEMRI. He holds a Master of Medicine in ENT/Head and Neck Surgery from the University of Nairobi and also a Diploma in Cancer Control from the National Cancer Institute (USA).

He has been involved in Head and Neck Cancer Epidemiology at the Centre for Clinical Research, the Pathology Oncology Research Unit and Nairobi Cancer Registry NCR). He has been instrumental in the profiling of the cancer resist through technical and clinical advice to the NCR over the years. This had included cancer policy through the ministry of health and other stakeholders including the most recent Blue print for Success under Takeda Pharmaceuticals. He has also been a facilitator of the Cancer Registrar training over the years.

VIEW ALL STAFF PROFILES

Contact Info

Kenya Medical Research Institute Headquarters, 

Nairobi. off Mbagathi way,

P.O BOX 20778 – 00200 Nairobi

Tel: 2720781

E-mail: ccr@kemri.org

Location