CENTRE FOR TRADITIONAL MEDICINE AND DRUG RESEARCH. (CTMDR) NAIROBI.

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Overview

Center for Traditional Medicine Research (CTMDR) is a centre within Kenya Medical Research
Institute (KEMRI) mandated to carry out research to rationalize traditional medicine in Kenya
and, to carry out quality assurance of conventional medicine.
The centre is headed by a Deputy Director, who oversees five units.
The units include:
1. Chemical sciences
2. Biological sciences
3. Pharmaceutical sciences
4. Botanical sciences
5. Administration
The units are headed by unit heads who report to the Deputy Director.

Mission

To be a leading centre of excellence in the promotion of quality and safe use of traditional medicines and drugs for quality health.

Mission

To improve on the quality of health and human life by providing scientific evidence based information on traditional medicines and drugs.

Mandates

    1. Traditional Medicine
    • Rationalization of traditional medicines in collaboration with traditional healers; evaluation of plant drugs using medicinal Phytochemistry, pharmacology and toxicology and, formulation of herbal remedies.
    • Studies on agents for the control and management of Infectious, Parasitic and Non-Communicable Diseases in addition, Socio-cultural and anthropological aspects of traditional medicine.
    1. Drugs
    • Quality assurance through; Surveillance, experimental pharmacology and toxicology; biopharmaceutics and pharmacokinetics; clinical trials.
    1. To collaborate with other KEMRI centres, local, regional and international institutes and organizations to be able to carry out all the above mandates.

Core Values

  1. Sanctity of life: We value life and endeavor to preserve and improve it.
  2. Creativity and innovation: We are committed to promoting and supporting creativity and innovation through research.
  3. Equity and quality: We employ the highest professional conduct possible to achieve high standards of service delivery.
  4. Acceptable corporate Governance: We employ the best practices and principles of good governance.
  5. Team work: At CTMDR we are a team and we operate as such.

PARTNERS AND COLLABORATORS

The Center serves and collaborates locally, regionally and internationally with many clients that include research scientists, students, and patients among others.

The clients or collaborators, interested in training, advice and research on medicinal plants, development of drugs or quality evaluation of drugs, include:

  1. Educational institutes such as Jomo Kenyatta University of Agriculture and Technology, Kenyatta University, University of Nairobi, Maseno University, Makerere University, University of Dar es Saalam, Muhimbili University, and University of Ibadan, Cameroon University, University of Cape Town, USIU-Africa, Karatina University, Egerton University, MKU.
  2. Research institutes and organizations such as International Centre of Insect Physiology and Ecology (ICIPE), Kenya Agricultural Research Institute (KARI), Kenya Industrial Research Development Institute (KIRDI), National Museums of Kenya, Institute of Primate Research (IPR), Japan International Cooperation Agency (JICA), World Health Organization (WHO), Wellcome Trust Laboratories.
  3. Ministries of Health (Medical Services and Public Health and Sanitation).
  4. Ministry of Culture and Social Services (Department of Culture).
  5. Traditional Health Practitioners (THPs).
  6. Students and Researchers from all corners of the world.

Ongoing Projects

  • The Pyrethrum Project (SSC No. 2969) – There are 11 nested proposals under the Pyrethrum project with full approval from SERU.
  • The Miraa Project (SSC No. 2949).

Completed Projects

DIVISIONS

  1. CHEMICAL SCIENCES

  2. BIOLOGICAL SCIENCES

  3. PHARMACEUTICAL SCIENCES

  4. BOTANICAL SCIENCES

  5. ADMINISTRATION DIVISION

  6. ENTERIC DIVISION

  7. MYCOLOGICAL AND AMR

  8. OPPORTUNIST INFECTIONS AND GENOMICS DIVISION

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DR. FESTUS M. TOLO-Head, NAPREDA, KEMRI

Dr. Festus M. Tolo is a Phyto-Medical biologist holding a Doctor of Philosophy Degree in Medicinal Phytochemistry of Jomo Kenyatta University of Agriculture and Technology (JKUAT). He is a fellow at the African Scientific Institute (ASI) and an a awardee of the “The Nelon Gold Award (NGA)” of the Kenya Medical Research Institute (KEMRI) and the Inter-Academy Medical Panel (IAMP) “Distinguished Scientist Award in Natural Products Research” of the Chinese Medical Sciences (CACMS) and Chinese Academy of Engineering (CAE), China.
Dr. Tolo is a Chief Research Officer and the Head of the Natural Products Research and Drug Development Programme (NAPREDA) at KEMRI. His engagements in natural products research spans over two decades where he has been involved in various research projects, notably, the JICA sponsored Infectious Diseases Research Programme of KEMRI where he played a key role in the “Plant Drug Research Group for Antiviral Agents” leading to the innovation of an anti-herpes herbal product, Zedupex.
He has been a project manager of a WHO/TDR funded project on the “Investigation of Safety, Efficacy and Chemistry of Herbal Medicines used Traditionally for Treatment of Malaria” and a lead scientist in the National Council for Science Technology and Innovation (NACOSTI) funded project on the “Natural Products Innovation System: Establishing a National Nutraceuticals and Phytomedicines Development Pipeline”.
He is presently engaged in a project evaluating Pyrethrum for new biomedical uses in human health funded by the Government of Kenya. Dr. Tolo has published widely in the area of natural products research and presented over 35 research abstracts at various local and international scientific forums. He is a part time lecturer in Medical Microbiology at JKUAT Karen campus and faculty at the KEMRI Graduate School. He has successful supervised a number of post graduate students both at PhD and MSc. He is an appointed peer reviewer of Quality Standards (QS) by the Commission for University Education (CUE), Kenya.

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Dr. Elizabeth V. Mumbi Kigondu-Senior Research Scientist

Academic qualifications
• PhD. Chemistry
• MSc. Medicinal Chemistry
• BSc. Chemistry

Research interests
• Natural products and chemical synthesis drug discovery research
• Drug and chemical analysis
• Nutrition from natural products

Publications
1. Elvis K. Muthoni, Elizabeth M. Kigondu, Daniel Kiboi, Ibrahim N. Mwangi. Efficacy and Safety of Up-scaled Dosage of 60mg/kg Praziquantel in Control of Schistosoma mansoni in School Going Children in Kirinyaga County, Kenya. International Journal of Tropical Disease & Health. Vol 33(4), pp 1-12, December 2018.
2. Elizabeth V. M. Kigondu, Moses K. Kamita, Elizabeth W. Njenga, James Wanga, Gabriel Amalemba, Esther N. Matu. In vivo Antifertility and Safety Profiles of Kenyan Moringa oleifera Lam. (Moringaceae) extracts. African Journal of Pharmacology and Therapeutics Vol. 5(4), pp 212-220, December 2016.
3. Ruth M. Nyangacha, Peter M. Mathiu, Moses Mwangi, Elizabeth V. M. Kigondu Antinociceptive effect of Pentas lanceolata and Ximenia americana medicinal plants used to treat malaria traditionally in Kenya. African Journal of Pharmacology and Therapeutics. Vol. 5(2), pp 87-92, July 2016.
4. Ken-Ichi Umehara, Markus Zollinger, Elizabeth Kigondu, Marc Witschi, Claire Juif, Felix Huth, Hilmar Schiller, Kelly Chibale, Gian Camenisch. Esterase phenotyping in human liver in vitro:specificity of carboxylesterase inhibitors. Xenobiotica. Early Online: 1–6, February 2016.
5. Charles K. Rotich, Ruth M. Nyangacha, Sabina W. Wachira, Moses M. Ngeiywa, Elizabeth V. M. Kigondu. Antimalarial activities and toxicity levels of selected medicinal plants used in Kenya. African Journal of Pharmacology and Therapeutics. Vol. 4(3), pp 92-100, August 2015.

Contact Info

Traditional Medicine and Drug Development Programme,

Kenya Medical Research Institute,

P.O Box, 54840-00200, Nairobi, KENYA

Office Tel: (254) (020) 2722541, Ext. 3324

Fax: (254) (020) 2720030

Email: Director@kemri.org Website: www.kemri.or

Location