CENTRE FOR VECTOR DISEASE CONTROL-KWALE
The Kwale Research Centre is responsible for conducting fundamental and applied research on vector-borne parasites and viruses of medical importance, the insect vectors of these pathogens, and immunology, parasitic infections surveillance, epidemiology and Molecular Biology.
1. Vector Biology Division (Disease transmission Dynamics)
(i) To carry research on mosquitoes and mosquito-borne diseases
(ii) To Undertake research on Snails and its ecology
(iii) Undertake vector Surveillance
(iv) Integrated Vector Management and Control (pre-elimination, elimination, eradication)
(v) To map Insecticide Resistance and understand its impact on malaria transmission
(vi) To understand Vector-pathogen interactions
(vii) To understand vector ecology
(viii) To understand population genetics of mosquitoes
(ix) Emerging and Re-emerging infectious diseases (Dengue, Chikungunya, Zika, Rift Valley Valley)
(x) Mosquito containment (Insectary and mosquito experimental huts)
2. Biomedical Research Division (Parasitic and Microbial Disease Epidemiology, Immunology and Molecular Biology)
(i) To understand the epidemiology malaria in populations
(ii) Understand Schistosomiasis in the community and predisposing factors
(iii) Epidemiology and surveillance
(iv) Anti-microbials, screening & resistance
(v) Antimicrobial drug resistance monitoring and surveillance
(vi) Molecular characterization of microbes
(vii) To Understand human immunological responses to disease
(viii) Human Anopheles-Plasmodium genomics
(ix) Parasitic systems biology
(xi) Whole Genomic analysis and Proteomics
(xii) Diagnostics, development/improvement of diagnostic tools, testing/evaluations of new tools
3. Diagnostics Laboratory and support of County Health Clinical Care
(i) Diagnosis of parasitic and infectious diseases
(ii) Diagnosis of Microbes
(iii) To undertake haematological analysis
(iv) To undertake urinalysis
(v) To provide biochemistry analysis of human samples
(vi) To support clinical care of the clients at Kwale County hospital and Clinical Research teams
VECTOR BIOLOGY RESEARCH DIVISION
In Kwale County malaria transmission has been persistent during this Phase of scaled up interventions through continuous and regular distribution of long-lasting impregnated nets (LLINs). This has resulted in high malaria morbidity and mortalities especially in children under 5 years and pregnant women. Besides malaria, there is an upsurge of emerging and re-emerging arboviral diseases such as dengue fever, chikungunya, rift valley fever which calls for strengthening of surveillance and research on mosquitoes and mosquito-borne diseases in Kwale.
(i) Malaria Transmission and epidemiology
(ii) Insecticide Resistance in mosquitoes
(iii) Emerging and Re-emerging diseases such as ZIKA, Dengue, Chikungunya
(iv) Neglected Tropical Diseases transmitted by mosquitoes such as Filariasis
(v) Schistosomiasis and Soil Transmitted Helminths (STHs)
BIOMEDICAL RESEARCH DIVISION
The Division is responsible for undertaking research in Parasitic and Microbial Disease, Epidemiology, Immunology and Molecular Biology.
(i) Parasitic and Microbial Disease Epidemiology,
(ii) Immunology and Molecular Biology
(iii) Host-Parasite interactions
DIAGNOSTICS LABORATORY AND SUPPORT OF COUNTY HEALTH CLINICAL CARE DIVISION
The Diagnostics laboratory is responsible for Planning and supporting research activities in the Centre through coordination, supervision and participation in sample collection, analysis and dissemination of quality assured results to improve human health.
These laboratories are classified as follows:
- i) Haematology Laboratory: Haematology is concerned with diagnosis of diseases related to blood. The laboratory work that goes into the study of blood is frequently performed by a Medical Technologist or Medical Laboratory Scientist. Including analysis of factors concerned with oncology.
(ii) Parasitology Laboratory: Parasitology laboratory offers a referral service for the identification of a wide range of human parasites from clinical specimens. Examples of tests include Blood Parasite diagnosis: Malaria, African Trypanosomes and Filariasis, Faecal Parasite diagnosis: Faecal microscopy direct examination and / or concentration for parasites (including hot stool), Culture for Strongyloidiasis / Hookworm, Faecal staining methods, Enterobius microscopy. Urinalysis using urine analysis techniques and filtration for schistosomiasis.
(iii)Clinical Chemistry Laboratory: Clinical Chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is the area of clinical pathology that is generally concerned with analysis of bodily fluids for diagnostic and therapeutic purposes as well assessment of toxicology. The Centre will carry out Clinical Research focusing on clinical work based on Kwale County Hospital to understand disease profiles and investigating the transmission patterns: The Clinical Research Laboratory will be based on the existing Laboratory facility in Kwale County Hospital. This laboratory will need to be renovated and modernized to ensure it could handle support diagnostic laboratory work. The diagnostic support will include the Parasite detection (Malaria, STHs), Liver/kidney functions, urinalysis, blood profiles, Microbiology, antibiotic drug resistance and sensitivity profiles.
. RESEARCH SUPPORT STATIONS
Msambweni and Kinango Field Stations
To properly ensure proper coordination of Biomedical and Clinical Research with Kwale, two (2) field stations, Msambweni and Kinango will coordinate field work for sample collections and will be the main reference points for community engagement and community entry, sample sorting and analysis and liaison with the County Department.
Diani and Lunga Lunga Satellite Stations
These two satellite sites will oversee specific research questions data collections. Diani and Lunga Lunga Satellite will be responsible for Emerging and Re-emerging disease surveillance especially mosquito borne arboviral infections such as Chikungunya, Dengue Fever, Yellow Fever and Zika. These sites are also key in monitoring urbanization and possible associated diseases.
- SUPPORT SERVICES SECTION
The station will have the following support services and staffing to ensure prudent management of Institutes Resources and prompt and timely Reporting, including Monitoring and Evaluation (M&E). The Support Services will be under the Office of the Deputy Director.
(iii) Information Communication Technology
(iv) Accounts and Finance
(v) Facilities and Maintenance
(vi) Security services