Eastern and Southern Africa Centre of International Parasite Control (ESACIPAC)

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Overview

Eastern and Southern Africa Centre of International Parasite Control (ESACIPAC) was established in May 2001 with the goal of coordinating activities on school health based parasite control in the Eastern & Southern Africa region under the framework of the Global Parasite Control Initiative (also called Hashimoto initiative). Japan successfully eliminated major parasitic diseases, including malaria, lymphatic filariasis, schistosomiasis and intestinal worms using a school health based approach. Based on this experience, the Government of Japan in 1998 proposed the Hashimoto initiative and established three research and training centres around the world – in Asia, East Africa, and West Africa.

The Kenya Medical Research Institute (KEMRI) officially inaugurated ESACIPAC as a research and training centre of the institute in 2002 to ensure its sustainability and as a strategy to improve KEMRI’s contribution to capacity building for human health improvement through supporting parasite control activities in the region.

Although the Hashimoto Initiative stopped abruptly in 2008, the Centre has made major strides forward realizing substantial growth in number of projects and diversity of activities undertaken. New partnerships and collaborations have been established ensuring that ESACIPAC continues to be a regional Centre of excellence in parasite control

Mission

To be a leading Centre of excellence in human health research and capacity development aimed at improving the quality of life of people affected by parasitic diseases.

Vision

To be a regional centre of excellence

Mandates

    • articipation in prevention and control of parasitic diseases through,
      • Evaluation of tools and strategies for parasite control
      • Public health and social science research
    • Strengthening regional capacity for school health and nutrition through,
      • Workshops/ Training courses
      • Technical meetings
      • Technical assistance in the implementation of public health programmes
    • Strengthening partnerships for research, training and capacity building in parasite control through,
      • Supporting development of guidelines and strategic plans
      • Establishment of a reference regional NTD laboratory
      • Training students from local universities
    • Sharing best practices for prevention and control of parasitic diseases through operation research in malaria and NTDs including schistosomiasis, soil-transmitted helminths and lymphatic filariasis

Products and Services

  1. Specialized technical services to research projects and public health programmes
  2. Training facilities and services
  3. Technical support to Ministry of Health

Core Values

  1. Sanctity of life:We uphold and respect sanctity of life
  2. Creativity and Innovation:We are committed to promoting and supporting creativity and innovation
  3. Professionalism:We are committed to excellence and the highest standards of professionalism
  4. Good Corporate Governance:We believe in the principles of good corporate governance and best practices
  5. Customer focus:We value our customers, and we endeavor to be customer focused
  6. Teamwork:We believe there is strength in teamwork and therefore, we encourage team spirit in what we do.

Ongoing Projects

COMING SOON

Completed Projects

COMING SOON

PARASITOLOGY AND ENTOMOLOGY DIVISION

To conduct research on parasitic diseases particularly malaria and NTDs, to evaluate tools and strategies for parasite control, to work with the Ministry of Health in mapping and surveillance (epidemiology) for parasitic diseases. To conduct monitoring and evaluation for Ministry of Health School-based and community-based parasite control and elimination programmes.

IMMUNOLOGY AND SERELOGY

To evaluate tools and strategies for parasite control, to provide NTDs research diagnostic services.

MOLECULAR BIOLOGY

To evaluate tools and strategies for parasite control, to provide NTDs research diagnostic services

PUBLIC HEALTH AND SOCIAL SCIENCES

To conduct implementation research for preventive chemotherapy NTDs targeted for control and/elimination by the Ministry of Health and other ministries as well as malaria.

Proposals and Manuscripts
Henry M. Kanyi
Proposals as a Principle Investigator (P.I)
1. Molecular assessment of malaria infection burden and antibody responses in pregnant mothers and children attending health facilities in Kwale and Siaya malaria endemic Counties in Kenya. SERU No. 3422. Funder: GOK IRG
Proposals as a Co-Principle Investigator (Co-P.I)
1. Responding to Gender and Age Needs in Prevention and Management of Drug and Substance Abuse in selected Counties of Kenya through the Health System. SERU 3237: KEMRI GOK/IRG funded
2. An assessment of integration of health services for women and children <5 years of age within health facilities including beyond zero mobile clinics in two malaria endemic zones of Siaya and Kwale in Kenya. SERU 3252: KEMRI GOK/IRG funded
3. An explorative study on the associations between Titanium mining activities and malaria transmission in Kwale County, Coastal Kenya. KEMRI GOK/IRG funded
4. When is it appropriate to stop? Applied field research to develop an M&E strategy to guide decisions for stopping triple drug intervention against lymphatic filariasis in Kenya. SERU 3721. Funded by Task force for Global Health, Atlanta, USA
5. Establishment of a platform for development of diagnostic tests for Schistosomiasis. Awaiting Approval. Funded by FIND international, Switzerland

Manuscript
1. Jane W. Wanyiri, Henry Kanyi, Samuel Maina, David E. Wang, Paul Ngugi, Roberta O’Connor, Kimani Gachuhi, Mkaya Mwamburi, Njeri Wamae, Honorine D. Ward. Infectious diarrhea in antiretroviral therapy-naïve HIV/AIDS patients in Kenya. Royal Society of Tropical Medicine and Hygiene 2013; 107: 631–638.
2. Jane W. Wanyiri, Henry Kanyi, Samuel Maina , David Wang, Timothy Kamau , Kimani Gachuhi, Njeri Wamae , Roberta O’Connor , Mwamburi Mkaya and Honorine Ward . Cryptosporidiosis in HIV/AIDS patients in Kenya: Clinical Features, Epidemiology, Molecular Characterization and Antibody Responses. American Journal of Tropical Medicine and Hygiene 91(2), 2014, pp. 319 – 328
3. Parminder S. Suchdev, Stephanie M. Davis, Laird J. Ruth, Monina Bartoces, Caitlin M. Worrell, Henry Kanyi, Ryan E. Wiegand, Sammy M. Njenga, Joel M. Montgomery, LeAnne M. Fox. Soil-transmitted helminth infections and nutritional status among urban slum children in Kenya. American Journal of Tropical Medicine and Hygiene 90(2), 2014, pp. 299 – 305
4. Kanyi Henry, Mutungi M. Faith, Chieng Benard, Araka Sylvie, Caitlin M. Worrell, Sukwan Handali, Sammy M. Njenga, Julie R. Harris. Infection with Strongyloides stercoralis among children in urban slums of Kibera in Nairobi, Kenya. Afr, J of H Sci. Feb 2016.
5. Sammy M. Njenga; Henry M. Kanyi; Faith M. Mutungi; Collins Okoyo; Hadley S. Matendechero; Rachel L. Pullan; Katherine E. Halliday; Simon J. Brooker; C. Njeri Wamae; Joyce K. Onsongo; Kimberly Y. Won. Assessment of Lymphatic Filariasis Prior to Re-Starting Mass Drug Administration Campaigns in Coastal Kenya. Parasite & Vectors. 2017 Feb 22;10(1):99. doi: 10.1186/s13071-017-2044-5.
6. Won, Kimberly; Henry M. Kanyi; Mwende, Faith; Wiegand, Ryan; Goodhew, Brook; Priest, Jeffrey; Lee, Yeuk-Mui; Njenga, Sammy; Secor, William; Lammie, Patrick; Odiere, Maurice. Multiplex Serologic Assessment of Schistosomiasis in Western Kenya: Antibody Responses in Pre-school Age Children as a Measure of Reduced Transmission. American Journal of Tropical Medicine and Hygiene. DOI: https://doi.org/10.4269/ajtmh.16-0665
7. Bartholomew N. Ondigo, Erick M. O. Muok, John K. Oguso, Sammy M. Njenga, Henry M. Kanyi, Eric M. Ndombi1, Jeffrey W. Priest, Nupur Kittur, William Evan Secor, Diana M. S. Karanja and Daniel G. Colley. Impact of Mothers’ schistosomiasis status during gestation on children’s IgG antibody responses to routine Vaccines 2 Years later and anti-schistosome and anti-Malarial responses by neonates in Western Kenya (2018). Front. Immunol. 9:1402. doi: 10.3389/fimmu.2018.01402
8. E. Mulinge, S.M. Njenga, D. Odongo, J. Magambo, E. Zeyhle, C. Mbae, D. Kagendo, H. Kanyi, R.J. Traub, M. Wassermann, P. Kern and T. Romig. Molecular identification of zoonotic hookworms in dogs from four counties of Kenya (2019). Journal of Helminthology 1–8. https:// doi.org/10.1017/S0022149X1900018X
9. Henry Kanyi, Collins Okoyo, Kimberly Y. Won, Jeffrey W. Priest and Sammy M. Njenga. Comparative assessment of Wuchereria bancrofti infection using Wb123 ELISA and multiplex bead assay techniques in lymphatic filariasis endemic coastal region of Kenya: a cross-sectional study. Tropical Medicine and Infectious diseases. Under development and review
10. Njenga, Sammy. Kanyi, Henry. Arnold, Benjamin. Matendechero, Sultani. Onsongo, Joyce. Won, Kimberly. Priest, Jeffrey. Integrated cross-sectional multiplex serosurveillance of IgG antibody responses to parasitic diseases and vaccines in coastal Kenya. American Journal of Tropical Medicine & Hygiene – AJTMH-19-0365. Accepted for publication

LIST OF FUNDED PROJECTS

1. Non-Reseacrh Project on Home grown school-feeding in Kilifi, Kitui and Tharaka Nithi (Mwandawiro- PI) 100 Million
Source: PCD Imperial College
2. KEMRI SERU (being reviewed) (Mwandawiro PI)
Evaluation of the effectiveness of IVERMECTIN/Albendazole co-formulation vs ALBENDAZOLE for treatment of worms (STOP) 86 Million KShs
Source: EDTCP, Barcelona
3. KEMRI SERU 3873: (Mwandawiro Co-PI)
An evaluation of Trichuris trichiura prevalence in Kwale County 2.224M Kshs
Source: African Research Network for Neglected Tropical Diseases (ARNTD)

4. KEMRI SERU 3822 (Mwandawiro PI)
An evaluation of malaria infection among primary school children in nine counties of Western Kenya and the Coast 18 Million Kshs
Source: WT Kilifi

5. KEMRI SSC 2206 (Mwandawiro, PI)
National School-Based De-worming in Kenya: Five Year Monitoring and Evaluation of the Programme Impact 180 Million Kshs
Source: Childrens’ Investment Fund Foundation (CIFF)) & END Fund

6. KEMRI SSC 2826 (Mwandawiro Co-PI)
Interrupting transmission of soil-transmitted helminths: a study protocol for cluster randomised trials evaluating alternative treatment and delivery strategies in Kenya (34 million Kshs.)
Source: Bill &Melinda Gates Foundation

7. Maping of Schistosomiasis in Machakos, Kitui, Makueni and Wajir counties (28 million Kshs.)
Source: END Fund

8. KEMRI SSC 1407 (Mwandawiro, PI) 22/05/2008
Epidemiological support to Kenya’s National School Health Programme (SHNP) (45 million Kshs.).
Source: Bill &Melinda Gates Foundation

9. KEMRI/JICA RD 2006: (Mwandawiro, PI) 13/05/2006
KEMRI/JICA School-based parasite control project in Mwea, Central Kenya (75 million Kshs)
Source: JICA

10. TDR Project ID A00564 (Mwandawiro, PI) renewed 02/06/2008
Trends in transmission and infection with Anopheles transmitted lymphatic filariasis during mass treatment (5 Million KShs)
Source: WHO/TDR

11. KEMRI SSC 1266 (Mwandawiro, PI) 04/06/07-08/11/07
Survey of the parasitic infections and anaemia among schoolchildren in Kwale District- A pilot survey (3 million Kshs)
Source: Wellcome Trust

12. Integrated Schistosomiasis and Soil transmitted Helminths Control Strategies in Kirinyaga County, Central Kenya. 5 Million KShs
Source: KEMRI-IRG

Dr. Doris Wairimu Njomo


“Responding to Gender and Age Needs in Prevention and Management of Drug and Substance Abuse in selected Counties of Kenya through the Health System” funded by Government of Kenya, KEMRI Health Research Funds 2015 to date
‘Evaluating Different Drug Delivery Approaches for Treatment of Soil-transmitted Helminthiasis and Schistosomiasis Infections in the National School-based Deworming Programme among Children Attending Early Childhood Development (ECD) Centers in Coast Province, Kenya’ funded by National Commission for Science, Technology and Innovation 2012/2013 STI Grant-October 2013 to date

Dr. CHARLES MWANDAWIRO SMITI


Dr. Charles Mwandawiro is a medical entomologist/parasitologist with over 20 years of experience in operational research and control of Neglected Tropical Diseases (NTDs). He has served as Assistant Director in charge of Partnership and Collaboration at KEMRI. Currently, he coordinates School Health and Nutrition activities, particularly school-based parasite control and school feeding. Dr. Mwandawiro has authored more than 35 publications in peer-reviewed journals covering the fields of entomology and the prevention and control of NTDs and malaria.

He holds a PhD in Medical Entomology (Institute of Tropical Medicine, Nagasaki University) and a Masters in Medical Parasitology from University of Nairobi.

KANYI HENRY MURIUKI


SELECTED PUBLICATIONS

1. Jane W. Wanyiri, Henry Kanyi, Samuel Maina, David E. Wang, Paul Ngugi, Roberta O’Connor, Kimani Gachuhi, Mkaya Mwamburi, Njeri Wamae, Honorine D. Ward. Infectious diarrhea in antiretroviral therapy-naïve HIV/AIDS patients in Kenya. Royal Society of Tropical Medicine and Hygiene 2013; 107: 631–638.
2. Jane W. Wanyiri, Henry Kanyi, Samuel Maina , David Wang, Timothy Kamau , Kimani Gachuhi, Njeri Wamae , Roberta O’Connor , Mwamburi Mkaya and Honorine Ward . Cryptosporidiosis in HIV/AIDS patients in Kenya: Clinical Features, Epidemiology, Molecular Characterization and Antibody Responses. American Journal of Tropical Medicine and Hygiene 91(2), 2014, pp. 319 – 328
3. Parminder S. Suchdev, Stephanie M. Davis, Laird J. Ruth, Monina Bartoces, Caitlin M. Worrell, Henry Kanyi, Ryan E. Wiegand, Sammy M. Njenga, Joel M. Montgomery, LeAnne M. Fox. Soil-transmitted helminth infections and nutritional status among urban slum children in Kenya. American Journal of Tropical Medicine and Hygiene 90(2), 2014, pp. 299 – 305
4. Kanyi Henry, Mutungi M. Faith, Chieng Benard, Araka Sylvie, Caitlin M. Worrell, Sukwan Handali, Sammy M. Njenga, Julie R. Harris. Infection with Strongyloides stercoralis among children in urban slums of Kibera in Nairobi, Kenya. Afr, J of H Sci. Feb 2016.
5. Henry Kanyi, Sammy Njenga, Jimmy Kihara, Collins Okoyo, Abdisalan Noor, Robert W Snow, Charles Mwandawiro. Rapid Diagnostic Test versus Polymerase Chain Reaction detection of Plasmodium falciparum: An evaluation of asymptomatic children from selected primary schools in Kilifi, Mombasa and Kwale counties, Coast region, Kenya. (Manuscript under Development).

Edward Githinji


Expert/Specialist in the following Research areas:
Entomology – mosquito & sand fly field & Insectory work; Malaria Vector Surveillance & Tungiasis control
Parasitology – P. falciparum, Leishmania major , Shistosoma spp, & STH field & laboratory work; Master trainer National School Based Deworming Programme
ITROMID KEMRI JKUAT Assistant Lecture

Contact Info

P.O. Box 54840, Nairobi, KENYA

Tel: +254-20-2731192/3, +254-20-2722541

Fax: +254-2-2717521, 2731194

Location